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Phendimetrazine Tartrate drug information

Generic Name: phendimetrazine (fen di MEH tra zeen) tartarate
Brand Names: Adipost, Anorex-SR, Appecon, Bontril PDM, Bontril Slow-Release, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex

Chemical name: 3,4-Dimethyl-2-phenyl-morpholine tartrate

Phendimetrazine tartrate, as the dextro isomer, has the chemical name of (2S.3S)-3, 4-Dimethyl-2-phenylmorpholine L-(*)-tartrate (1.1). Its molecular weight is 341.36.

Phendimetrazine tartrate is a white, odorless crystalline powder. It is freely soluble in water; sparingly soluble in warm alcohol, insoluble in chloroform, acetone, ether and benzene.

Each tablet, for oral administration, contains 35mg of phendimetrazine tartrate. In addition, each tablet contains the following inactive ingredients: Lactose USP, Magnesium Stearate NF, Colloidal Silicon Dioxide, Microcrystalline Cellulose NF, Starch NF (Modified Corn Starch).

Additional inactive ingredients are present as follows: Phendimetrazine 35mg Gray Tablet Contains: Activated Charcoal USP. Sterotex Food Grade.

Phendimetrazine 35mg Pink Tablet contains: FD&C Red #3.

Phendimetrazine 35mg Speckled Tablet contains: Calcium Stearate NF, FD&C Blue #1, FD&C Yellow #5, and sucrose.

Phendimetrazine 35mg Yellow Tablet contains: FD&C Yellow #5, Calcium Stearate NF.

Phendimetrazine 35mg Blue Tablet contains: FD&C Blue #1.

Phendimetrazine tartrate is indicated in the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction. The limited usefulness of agents of this class (see CLINICAL PHARMACOLOGY) should be measured against possible risk factors inherent in their use such as those described below.

Medicare proposes hospital outpatient pay rates (Reuters)
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Scientists: Watermelon yields Viagra-like effects (AP)
<p><a href="http://us.rd.yahoo.com/dailynews/rss/health/*http://news.yahoo.com/s/ap/20080703/ap_on_he_me/watermelon_viagra_effect"><img src="http://d.yimg.com/us.yimg.com/p/ap/20080702/capt.b810df103ac44eb89b2944b8f405418f.watermelon_viagra_effect_dn103.jpg?x=130&y=88&q=85&sig=H8.Wgzg3xvbJeHIChm4Dvg--" align="left" height="88" width="130" alt="A slice of watermelon is shown at the Gutierrez Produce stand at the Dallas Farmers Market, Tuesday, July 1, 2008, in Dallas. Watermelons contain an ingredient called citrulline that can trigger production of a compound that helps relax the body's blood vessels, similar to what happens when a man takes Viagra, said scientists in Texas. (AP Photo/Tony Gutierrez)" border="0" /></a>AP - A slice of cool, fresh watermelon is a juicy way to top off a Fourth of July cookout and one that researchers say has effects similar to Viagra — but don't necessarily expect it to keep the fireworks going all night long.</p><br clear="all"/>

Obesity may offer some protection after stenting (Reuters)
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Most study participants understand research goals (Reuters)
Reuters - People who take part in clinical trials often do so out of a desire to advance scientific knowledge and to help others, a new international study demonstrates.

First floods, now pesky mosquitoes for Midwest (AP)
<p><a href="http://us.rd.yahoo.com/dailynews/rss/health/*http://news.yahoo.com/s/ap/20080702/ap_on_he_me/med_mosquito_outbreak"><img src="http://d.yimg.com/us.yimg.com/p/ap/20080702/capt.a0650e8ee57840e3b0646e92543f4551.mosquito_outbreak_cx103.jpg?x=130&y=115&q=85&sig=s41lNZu6.wXSAiwRylOy7A--" align="left" height="115" width="130" alt="Dr. Anju Peters shows where a swarm of mosquitoes attacked her daughter Sonia, 7, last week leading to an outbreak of hives, swelling and a rash Wednesday, July 2, 2008, in Chicago. Heavy rains and warm temperatures that have hit the Midwest are creating ideal conditions for these bugs. (AP Photo\Russel A. Daniels)" border="0" /></a>AP - First came the floods — now the mosquitoes. An explosion of pesky insects are pestering clean-up crews and just about anyone venturing outside in the waterlogged Midwest.</p><br clear="all"/>

Some psych patients wait days in hospital ERs (AP)
<p><a href="http://us.rd.yahoo.com/dailynews/rss/health/*http://news.yahoo.com/s/ap/20080703/ap_on_re_us/marooned_psych_patients"><img src="http://d.yimg.com/us.yimg.com/p/ap/20080703/capt.2075a6a2e8b747629f2b4bcf504939fc.marooned_psych_patients_ny124.jpg?x=130&y=90&q=85&sig=n.VwVZPEkj7rHOgSaKHiaw--" align="left" height="90" width="130" alt="In this still photo taken from video provided by the New York Civil Liberties Union, Esmin Green lies face down on the floor in the psychiatric ward of the Kings County Hospital in Brooklyn, N.Y., Thursday, June 19, 2008. Green, 49, had been waiting in the emergency room for nearly 24 hours when she toppled from her chair at 5:32 a.m. and lay writhing, face down on the floor. Security guards and a member of the hospital's staff appeared to notice her prone body, but made no visible attempt to see if she needed help. Within an hour she was dead. (AP Photo/New York Civil Liberties Union)" border="0" /></a>AP - When staffers at a Brooklyn hospital spotted a middle-aged woman lying face-down on a waiting room floor last month, it hardly seemed like cause for alarm.</p><br clear="all"/>

Filipina with upside-down feet walks for 1st time (AP)
<p><a href="http://us.rd.yahoo.com/dailynews/rss/health/*http://news.yahoo.com/s/ap/20080703/ap_on_he_me/upside_down_feet"><img src="http://d.yimg.com/us.yimg.com/p/ap/20080702/capt.e8e42007a5e445ac8d301ff324e6bdaa.upside_down_feet_nyrd113.jpg?x=93&y=130&q=85&sig=qwOewVKC3mt3VWrWzh0WtQ--" align="left" height="130" width="93" alt="Jingle Luis, a 15-year-old girl from the Philippines who was born with severely clubbed feet, steps in to an elevator at New York's Montefiore Medical Center under the watchful eye of Dr. Terry Amaral, Wednesday July 2, 2008. Doctors took off her post-surgical casts and replaced them with special support braces and her first pair of shoes that allowed her to take her first unaided steps. (AP Photo/Richard Drew)" border="0" /></a>AP - A Filipino teenager who came to New York so doctors could perform surgery to untwist her severely clubbed feet took her first unaided steps Wednesday in pink-and-white sneakers — the first shoes she's ever worn.</p><br clear="all"/>

Lots of Sex May Prevent Erectile Dysfunction (HealthDay)
HealthDay - THURSDAY, July 3 (HealthDay News) -- Frequent sexual intercourse may cut down on a man's chances of developing erectile dysfunction, Finnish researchers report.

Kidney Cancer Vaccine Shows No Boost in Survival (HealthDay)
HealthDay - FRIDAY, July 3 (HealthDay News) -- The new vaccine vitespen didn't increase recurrence-free survival among kidney cancer patients who'd had surgery, say U.S. researchers.

Small babies may develop "fat" belly organs: study (Reuters)
Reuters - that is, significantly smaller than most babies born after the same number of weeks of pregnancy -- are prone to developing "visceral" adiposity (fatness) of the abdomen, even without being overweight, research hints.

Haywire brain chemical linked to sudden baby death (AP)
AP - Scientists have new evidence that the brain chemical best known for regulating mood also plays a role in the mystifying killer of seemingly healthy babies — sudden infant death syndrome.